The Use Of Silicone Products For Breast Implants - 2351 Words

Background Biomaterials, whether from natural or synthetic origin, have been used for many biomedical applications ranging from surgery to drug delivery (1). Of particular interest is the use of silicone products for breast implants, which are medical prostheses serving to augment or reconstruct breasts (1). To date, silicone is one of the most commonly used materials for plastic surgery procedures in North America (1, 2). The first silicone breast implants were developed in 1961 and were available for use by 1962. At that time, there was limited awareness on the safety and efficacy of silicone in breast implants, but this view changed when attention was drawn to repeated reports involving adverse reactions after implantation (1, 3-5). This led to a moratorium on silicone breast implants in 1992 by the US Food and Drug Administration (FDA) (5). After extensive research, the majority of results concluded that there were no major harmful effects associated with silicone products. In 2006, FDA app roved the use of silicone products in breast implants, which currently leaves silicone as the only available material for this purpose (3, 5, 6). Since that time, there has been controversy around the nature and associated complications related to silicone products in breast implants (1, 2, 5). This is reflected by the current body of literature, and seems to result from a lack of consistency in the methodologies used to determine the mechanisms underlying silicone transport, uptake,Show MoreRelatedEssay on Breast Implants1733 Words   |  7 Pages Breast Implants One of the first uses of silicone in a medical implant came in the form of lifesaving tubes implanted into young children to funnel excess fluid from the brain into the chest cavity, where the fluid could be safely metabolized and excreted. 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